ECHOCARDIOGRAPHIC FOLLOW-UP TO RIGHT VENTRICULAR MODIFICATIONS IN SECONDARY PULMONARY HYPERTENSION TO DIABETES IN RATS

Echocardiographic follow-up to right ventricular modifications in secondary pulmonary hypertension to diabetes in rats

Clinical studies suggest that diabetes is a risk factor in the development of pulmonary arterial hypertension.The increase in blood pressure in the pulmonary area is characterized by the increase in the afterload and hypertrophy of the right ventricle.The objective of this study was to conduct a longitudinal follow-up of the morphological and funct

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Elevated inflammatory responses and targeted therapeutic intervention in a preclinical mouse model of ataxia-telangiectasia lung disease

Abstract Ataxia-telangiectasia (A-T) is an autosomal recessive, multisystem disorder characterized by cerebellar degeneration, cancer predisposition, and immune system defects.A major cause of mortality in A-T patients is severe pulmonary disease; however, the underlying causes of the lung complications are poorly understood, and there are currentl

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The challenges of chronic urticaria part 1: Epidemiology, immunopathogenesis, comorbidities, quality of life, and management

This is Part 1 of an updated follow-up review of a World Allergy Organization (WAO) position paper published in 2012 on the diagnosis and treatment of RAW ORG. COCONUT OIL urticaria and angioedema.Since 2012, there have been advances in the understanding of the pathogenesis of chronic urticaria, and greater experience with the use of biologics, suc

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